Clinical study of digitalis.

Direct current shock and digitalis. A clinical and experimental study.

Measurement of serum digitalis glycosides: clinical implications.

The clinical use of digitalis preparations.

Digitalis and William Withering, the clinical investigator.

W ILLIAM WITHERING began to use digitalis for dropsical cases during 1775. The first recorded use of digitalis was on December 8 of that year when he administered a "decoction of fol. digital." to a man about 50 years of age who complained "of an asthma." As a result of the therapy, the patient "made a large quantity of water," " His breath gradually drew easier, his belly subsided, and in abou...

CLINICAL PROGRESS Digitalis and the Electrocardiogram

T HE action of digitalis and related glycosides is reflected in the electrocardiogram in a manifold fashion. Apart from altering the speed and mode of ventricular repolarization, represented by the ST-T portion, practically any type of disturbance in the formation or propagation of the cardiac impulse can result from digitalis medication; on the other hand some of these disorders of rhythm occu...